Wales have produced a remarkable 21-12 upset victory over the Wallaroos at Ballymore.
It came after a 30-minute delay due to lightning, forcing the teams off after 12 minutes.
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Fullback Nel Metcalfe crossed for a first-half double to give them the narrow lead at the break, holding strong in the second half to secure the win.
It will be one of two matches between the sides, with next week's game in Sydney set to be the final before Jo Yapp and the Wallaroos head to England for the hallmark event.
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Wales 21-12: The Wallaroos try for a late consolation try but the lineout isn't straight and Wales celebrate in style.
Wales 21-12: Another scrum penalty to the Wallaroos keep them in the contest.
But a tough bounce from a Lori Cramer chip kick sees the ball spill free and another turnover to Wales.
Wales 21-12: The Wallaroos have been camped inside Wales half but once again, just can't hang onto the ball.
Twice they hunt for a crucial try but drop the ball, summing up a tough afternoon so far.
Wales 21-12: Now or never for the Wallaroos as they are awarded another penalty, this time inside Wales' 22.
Both teams have basically emptied their benches, with Piper Duck and Sam Wood having an impact.
A penalty on the five metre line maintains Australia's momentum, lining up another maul, but the lineout is dropped.
Wales 21-12: The visitors hunt for the sealer as they break through the line, with the Wallaroos there to force the mistake.
A scrum just inside Wales' half gives the Aussies a great platform to start again
Wales 21-12: It feels like only a matter of time before the Wallaroos score.
A great burst from Piper Duck puts them inside Wales' 22, with another knock-on leading to a turnover.
They win a penalty on halfway that allows them to reload their attack.
Wales 21-12: The Wallaroos are finding themselves facing deja vu as a lack of breakdown control and handling lets them down.
They are enjoying a fair amount of territory with nothing to show for it, with the Welsh constantly clearing the pressure.
Wales 21-12: Remarkable, it's the Wallaroos scrum that is keeping them in this game.
They maul the Welsh back and force some chaos and a five metre scrum, but are again stung at the breakdown.
21-12 Wales: The Wallaroos are really struggling to play their style of Rugby in these wet conditions.
Another drop ball on the attack stifles their momentum, allowing Wales to hold on for now, with a great scrum winning Australia the tight-head and the penalty.
Unfortunately, it ends the same way: another Wallaroos handling error.
21-12 Wales: Wales have restored their lead as Hannah Dallavalle dives in the grubber for the try.
A beauty of a grubber from Lleucu George exposes the space at the back for Neumann to dive over untouched
14-12 Wales: A scrappy start from both teams as the visitors get the better of the Wallaroos.
The Wallaroos are struggling to make their passes stick in the wet conditions and presents a scrum to Wales inside the 22.
14-12 Wales: A crucial late try gives the Wallaroos the advantage heading into the break.
Tabua Tuinakauvadra capitalises on a strong rolling maul from close to the line as they trail by two.
14-7 Wales: Wales chip away and eventually have the lead right before half-time.
It's fullback Nel Metcalfe who finds the line after the visitors work through the hands for Metcalfe to score her second
7-all: Courtney Keight makes a brilliant run and Wales are back on the attack.
They build inside Australia's five metre line before the slippery ball leads to a knock on.
They win another penalty and find touch 15 metres out for their maul to set up an attack, with the Wallaroos holing one once again.
7-all: The Wallaroos are getting stung at breakdown time and it's costing them.
The hosts are looking the better side with ball in hand but they keep finding themselves isolated as Wales win penalty after penalty.
7-all: The Wallaroos nearly have themselves their second as Tia Hinds puts Kaitlan Leaney through a hole.
An excellent cover tackle from Lleucu George brings her down, with the Welsh able to get over the ball for the penalty.
A chargedown sets up a half chance for Wales, only for the visitors to fumble the pick up.
7-all: The hosts will put themselves in prime position after a high tackle on Desiree Miller.
It comes 40 metres out from the line, allowing the Aussies to kick for the line, but they fail to find touch.
Ash Marsters breaks clear of the defence a phase later, but the last pass from Emily Chancellor goes forward and the play breaks down 15 metres out.
7-all: Nel Metcalfe crashes over the line and Wales are on the board.
The halves hold up the defence perfectly for the fullback to dive over, with Desiree Miller's tackle strong but not enough to stop her.
7-0 Wallaroos: The rain is having its effects on the Wallaroos game as they drop the ball just crossing into Wales' half.
The hosts capitalise with a nice scrum play and win a penalty that puts them ten metres out.
Another penalty right on the line allows them to reset, with the attempted pilfer from the Aussies ending in a knock-on and a Wales five metre scrum.
Tia Hinds launches the drop out and play is back underway.
The rain is still coming down and it affects Wales as they drop the pill 22 metres out.
A great scrum for the Wallaroos allows the hosts to kick for the line.
We are back in action as the players slowly return to the field.
The two teams will go through their warm-ups as they look to pick up from where they left off.
We have an update, with the play set to return at approx. 2:46 pm AEST.
It will resume with a goal-line dropout to Australia.
It looks like the lightning is starting to leave the area but the rain is sticking around.
It's good news for this game, which should come back in the next 30 mins or so.
Here is what World Rugby dictates happens with lightning:
When the lightning strike is within 6 miles of the venue, it is recommended that players are removed from the pitch.
The speed of sound through air is approximately 0.2 miles per second, so for every 5 seconds of time between the lightning flash and the associated thunder clap, the strike is 1 mile away.
The approximate distance (in miles) can be calculated by counting the time (in seconds) between the two events and dividing it by 5. Recommended safe distances from the lightning event is 6 miles.
Recommendations on best practice also state that it should only be considered safe to return to the field of play a minimum of 30 minutes after the final flash of lightning or clap of thunder has been seen/heard.
Both teams are coming off the field as lightning stops play in the tough conditions.
The players will head into the dressing rooms as we wait for it to clear the area.
We will keep you updated as we here more.
7-0 Wallaroos: As predicted, the rain has settled into Ballymore as fans rush from the hill.
It proved catastrophic for the hosts as they missed their lineout from 10 metres out and suddenly Wales are on the attack.
The visitors get held up over the line, with the hosts surviving for now.
7-0 Wallaroos: You can only hold out the Wallaroos for so long as lock Annabelle Codey dives over on home soil in Queensland.
Ash Marsters thought she'd scored the opener but it's brought back for the penalty.
It allows Codey to crash over from close, just keeping possession as Desiree Miller makes the conversion.
The Welsh clear their line and get a prime chance to attack as their kick is dropped by the Aussies.
The visitors cross the 22 but Georgina Friedrichs comes up with the pilfer penalty and the danger is relieved.
Wallaoros turn to attack as they cross into Wales' half.
Tabua Tuinakauvadra gets the Aussies off to a flyer as the Wallaroos open the scoring. Or do they?
Tia Hinds sets up by drawing in the defence and finds the gap for the number eight to sprint away, but it seemed like there was a clear obstruction in the lead-up.
Yep, the TMO has found it in the replay and it's coming back, with captain Emily Chancellor the offender on Hannah Dallavalle.
The two teams are on the field and the anthems have been sung as the game gets underway.
There's rain threatening to hit midway through the game, with conditions holding off for now.
Welcome to Rugby.com.au's coverage of the first Test between the Wallaroos and Wales in Brisbane.
It looms as a massive fortnight for both sides as they ramp up their preparations for next month's Rugby World Cup.
Emily Chancellor gets the honour of representing Australia today - the 19th person to do so - while Wales are hunting for just their second win over the Wallaroos.
Tries: Codey, Tuinakauvadra
Cons: Miller 1/2
Tries: Metcalfe 2, Dallavalle
Cons: Bevan 3/3
Wallaroos (1-15): Lydia Kavoa, Katalina Amosa, Bridie O’Gorman, Kaitlan Leaney, Anabelle Codey, Emily Chancellor (c), Ash Marsters, Tabua Tuinakauvadra, Layne Morgan, Tia Hinds, Desiree Miller, Trilleen Pomare, Georgina Friedrichs, Waiaria Ellis, Caitlyn Halse
Replacements: Tania Naden, Bree-Anna Browne, Eva Karpani, Ash Fernandez, Piper Duck, Sam Wood, Cecilia Smith, Lori Cramer
Wales (1-15): Maisie Davies, Kelsey Jones, Donna Rose, Alaw Pyrs, Gwen Crabb, Georgia Evans, Bethan Lewis, Alex Callender, Keira Bevan, Lleucu George, Lisa Neumann, Courtney Keight, Hannah Dallavalle, Jasmine Joyce, Nel Metcalfe
Replacements: Molly Reardon, Katherine Baverstock, Sisilia Tuipulotu, Tilly Vucaj, Bryonie King, Seren Lockwood, Kayleigh Powell, Carys Cox
Referee: Maggie Cogger-Orr (NZR)
Assistant Referees: Natarsha Ganley (NZR) and Jess Ling (RA)
TMO: Rachel Horton (RA)
FPRO: Oli Kellett (RA)
The Wallaroos' clash with Wales will be shown LIVE on Stan Sport.
Coverage will be live and ad-free on Stan Sport, slated to start at 1:30 pm with kickoff expected at 2:00 pm.