South Africa prop Tendai Mtawarira will become only the second black player to represent the country 100 times when he lines up against England in Bloemfontein Saturday.
Bryan Habana, who retired this year, was the first to achieve the feat, making 124 Test appearances.
Victor Matfield, John Smit, Jean de Villiers and Percy Montgomery are the other Springbok centurions.
South Africa coach Rassie Erasmus hailed Mtawarira as "a great servant of the game" when he chose him for the second Test against England.
Zimbabwe-born Mtawarira was named Thursday in a team showing two changes from that which started a thrilling 42-39 first Test triumph over England in Johannesburg last Saturday.
Injury-plagued Frans Malherbe got the nod at tighthead prop in place of Wilco Louw, who Erasmus said was "punch-drunk" from playing so much rugby this year.
Flanker Pieter-Steph du Toit replaces Jean-Luc du Preez, giving South Africa an extra lineout option.
Former captain Chris Robshaw was axed for the first time by Eddie Jones as the England coach made two changes for a must-win second Test against South Africa Saturday.Blindside flanker Robshaw loses his place to New Zealand-born Brad Shields, who made his debut off the bench in a 42-39 first Test loss in Johannesburg last weekend.
England must win in Bloemfontein to stand a chance of taking a series in South Africa for the first time after five failed attempts.
The final match of the three-Test series in scheduled for Cape Town on June 23.
In the only other change to the starting line-up, fit-gain lock Joe Launchbury returns in place of Nick Isiekwe.
There are also two alterations to the bench with loose forward Mark Wilson and fly-half Danny Cipriani replacing Shields and Piers Francis.
TEAMS
South Africa to face England
1. Tenda Mtawarira
2. Bongi Mbonambi
3. Frans Malherbe
4. RG Snyman
5. Franco Mostert
6. Siya Kolisi
7. Pieter-Steph Du Toit
8. Duane Vermuelen
9. Faf De Klerk
10. Handre Pollard
11. Aphiwe Dyantyl
12. Damian de Allende
13. Lukhanyo Am
14. Sibusiso Nkosi
15. Willie Le Roux
Reserves
16. Akker van der Merwe
17. Steven Kitshoff
18. Thomas du Toit
19. Jean-Luc du Preez
20. Sikhumbuzo Notshe
21. Ivan van Zyl
22. Jesse Kriel
23. Warrick Gelant
England to face South Africa
1. Mako Vunipola
2. Jamie George
3. Kyle Sinckler
4. Joe Launchbury
5. Maro itoje
6. Brad Shields
7. Tom Curry
8. Billy Vunipola
9. Ben Youngs
10. George Ford
11. Mike Brown
12. Owen Farrell
13. Henry Slade
14. Jonny May
15. Elliot Daly
Reserves
16. Luke Cowan-Dickie
17. Joe Marler
18. Harry Williams
19. Mark Wilson
20. Nathan Hughes
21. Ben Spencer
22. Danny Cipriani
23. Denny Solomona
ARGENTINA VS WALES
Wales coach Warren Gatland continues his pre-Rugby World Cup experimenting in Argentina on Saturday by making five changes to the team that pulled off a shock first Test victory.
There are two backline alterations for the second and final Test in northeastern city Santa Fe with one enforced as inside centre Owen Watkin steps in for injured Hadleigh Parkes.
At scrum-half, Aled Davies takes over from Gareth Davies as the Welsh Dragons seek another success after winning 23-10 in San Juan last Saturday.
In the pack, hooker Ryan Elias comes in for Elliot Dee and tighthead prop Tomas Francis takes the place of Dillon Lewis.
The third change among the forwards is in the back row where Ellis Jenkins takes over from Seb Davies.
Lock Cory Hill continues as captain after making a winning debut in the role last weekend when dogged defending and clinical finishing laid the victory foundations.
TEAMS
Argentina to face Wales
Not yet announced
Wales to face Argentina
1. Rob Evans
2. Ryan Elias
3. Tomas Francis
4. Adam Beard
5. Cory Hill
6. Ellis Jenkins
7. James Davies
8. Ross Moriarty
9. Aled Davies
10. Rhys Patchell
11. George North
12. Owen Watkins
13. Scott Williams
14. Josh Adams
15. Hallam Amos
Reserves
16. Elliot Dee
17. Nicky Smith
18. Dillon Lewis
19. Bradley Davies
20. Josh Turnbull
21. Tomos Williams
22. Gareth Anscombe
23. Tom Prydie
New Zealand vs France
France can expect no respite in the second Test from the All Blacks, who are being urged by coach Steve Hansen to improve on a 41-point opening triumph.
Hansen has named an identical team to that which powered home late to prevail 52-11 at Eden Park for Saturday's clash in Wellington.
Concerned by their rusty start to the year in Auckland, where they trailed 11-8 at halftime, Hansen didn't want to halt the momentum that sparked seven tries in the last 27 minutes.
"We have a big focus right now on developing our game and working on our skill sets, connections and combinations," he said.
"It isn't beneficial to be making wholesale changes, if any at all, to the playing 23."
It means Sonny Bill Williams will need to wait until at least the third Test in Dunedin to return after the veteran inside centre underwent minor knee surgery last month.
Despite a massive impact from his bench last week, Hansen has resisted promoting any to the starting side.
Jordie Barrett is again one of three starting brothers and remains at fullback.
France have pinned their hopes on club form after announcing five changes to their starting team for the second Test against the All Blacks.
Coach Jacques Brunel deemed the three players involved in the Top 14 club final on June 2 would be off limits for last week's first Test in Auckland, which the tourists lost 52-11.
All three slot straight into his XV on Saturday at Westpac Stadium, including both flankers.
TEAMS
All Blacks to face France
1. Joe Moody
2. Codie Taylor
3. Owen Franks
4. Sam Whitelock
5. Scott Barrett
6. Liam Squire
7. Sam Cane
8. Luke Whitelock
9. Aaron Smith
10. Beauden Barrett
11. Rieko Ioane
12. Ryan Crotty
13. Anton Lienert-Brown
14. Ben Smith
15. Jordie Barrett
Reserves
16. Nathan Harris
17. Karl Tu'inukuafe
18. Ofa Tu'ungafasi
19. Vaea Fifita
20. Ardie Savea
21. TJ Perenara
22. Damian McKenzie
23. Ngani Laumape
France to face All Blacks
1. Dany Priso
2. Camille Chat
3. Uini atoni
4. Bernard le Roux
5. Yoann Maestri
6. Mathieu Babillot
7. Kelian Galletier
8. Kevin Gourdon
9. Morgan parra
10. Anthony Belleau
11. Gael Fickou
12. Geoffrey Doumayrou
13. Mathieu Bastareaud
14. Teddy Thomas
15. Benjamin Fall
Reserves
16. Pierre Bourgarit
17. Cyril Baille
18. Cedate Gomes Sa
19. Paul Gabrillagues
20. Alexandre Lapandry
21. Baptiste Serin
22. Jules Plisson
23. Maxime Medard
USA vs SCOTLAND
Stuart Hogg will captain Scotland for the first time when they take on the USA in Houston.
Dark Blues head coach Gregor Townsend has named a revamped starting XV following last weekend's 48-10 win over Canada - with seven players set to win their first caps.
Hogg's Glasgow teammates Matt Fagerson and George Horne will make their international bows alongside their elder brothers, with back-rower Fagerson joined by prop Zander and halfback Horne lining up alongside inside centre Pete.
There will also be debuts for the Glasgow trio Jamie Bhatti, George Turner and Adam Hastings, as well as Edinburgh's Lewis Carmichael and Luke Hamilton.
"We always planned to play as much of the squad as possible on this tour, and we also deliberately picked more Edinburgh players in the first game because their season finished earlier," Townsend - who has changed all but three of the side that thrashed the Canadians in Edmonton last weekend - said.
"Now we welcome most of the Glasgow Warriors contingent into the team. On top of that there are seven players making their first starts for the country, which is really exciting, and we are looking forward to them going out and grabbing this opportunity."
The Edinburgh pair of Ben Toolis and Blair Kinghorn as well as Sale wing Byron McGuigan are the only players to retain their places at the home of Major League Soccer outfit Houston Dynamos.
Saturday's match will be only the eighth time in close to 700 Scotland Tests when two sets of brothers have been on the field at the same time.
TEAMS
USA to face Scotland
Not yet announced
Scotland to face USA
1. Jamie Bhatti
2. George Turner
3. Zander Fagerson
4. Lewis Carmichael
5. Ben Toolis
6. Tim Swinson
7. Luke Hamilton
8. Matt Fagerson
9. George Horne
10. Adam Hastings
11. Byron McGuigan
12. Pete Horne
13. Nick Grigg
14. Blair Kinghorn
15. Stuart Hogg
Reserves
16. Fraser Brown
17. Alan Dell
18. Murray McCallum
19. Grant Gilchrist
20. David Denton
21. Sam Hidalgo-Clyne
22. Mark Bennett
23. Dougie Fife
JAPAN vs ITALY
Italian coach Conor O'Shea has made two changes to his starting line-up for Saturday's second rugby Test against Japan.
Jayden Hayward returns at fullback, pushing Matteo Minozzie to the left wing in place of the injured Mattias Bellini.
Among the forwards, Jake Polledri takes over at open-side flanker from Giovanni Licata.
Leonardo Ghiraldini again will captain Italy from hooker in his 96th Test, combining in the front row with Tiziano Pasquali and Andrea Lovotti. Lock Alessandro Zanni, in his 106th Test, moves up to fourth on Italy's list of Test appearances.
In contrast, prop Cherif Traore has been named to make his Test debut from the bench in Kobe.
Japan lead the two-Test series 1-0 after winning the opener 34-17 but Italy hold an overall 5-2 lead in matches between the countries.
TEAMS
Japan to face Italy
1. Keita Inagaki
2. Shota Horie
3. Ji-Won Koo
4. Wimpie Van Der Walt
4. Samuela Anise
6. Yoshitaka Tokunaga
7. Michael Leitch
8. Kazuki Himeno
9. Fumiaki Tanaka
10. Yu Tamura
11. Kenki Fukuoka
12. Timothy Lafaele
13. Will Tupou
14. Lomano Lemeki
15. Kotaru Matsushima
Reserves
16. Yusuke Niwai
17. Shintaro Ishihara
18. Takuma Asahara
19. Uwe Helu
20. Amanaki Mafi
21. Yutaka Nagare
22. Rikiya Matsuda
23. Ryoto Nakamura
Italy to face Japan
1. Andrea Lovotti
2. Leonardo Ghiraldini
3. Tiziano Pasquali
4. Alessandro Zanni
5. Dean Budd
6. Sebastian Negri
7. Jake Polledri
8. Abraham Steyn
9. Marcello Violi
10. Tommaso Allan
11. Matteo Minozzi
12. Tommaso Castello
13. Michele Campagnaro
14. Tommaso Benvenuti
15. Jayden Hayward
Reserves
16. Luca Bigi
17. Cherif Traore
18. Simone Ferrari
19. Marco Fuser
20. Giovanni Licata
21. Tito Tebald
22. Carlo Canna
23. Giulio Bisegni