France will take on a World XV featuring England's Vunipola brothers Mako and Billy and Fijian centre Semi Radradra in Bilbao ahead of their summer tour to South America, the French federation announced on Tuesday.
The fixture will be played on June 22 at the San Mames stadium in the northern Spanish port when many of France's top players will be involved in the Top 14 semi-finals.
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Former New Zealand coach Ian Foster and current Montpellier coach Patrice Collazo will take charge of the World XV, which will feature a number of players from Bayonne.
This includes former France half-backs Maxime Machenaud and Camille Lopez and prop Tevita Tatafu, provided the Basque club do not qualify for the last four of the Top 14.
"We are building an impressive squad," Foster said in a federation statement.
"When we take on the French XV in the Basque Country, we will certainly have the ambition to put on a show of attacking rugby."
France's tour of South America includes two Tests against Argentina and one against Uruguay.
“We are pleased to be able to announce today this very high-level international match in Bilbao," Jean-Marc Lhermet, Vice-President of the French Rugby Federation (FFR) said.
"Our French team is a magnificent tool for exporting rugby to countries where our sport continues to grow.
"It is a pride and a privilege to participate in its development. We can’t wait to see this magical stadium filled with the massive atmosphere that Basque supporters know how to create”.
“The selection of Spain as the venue to host a match of the highest international level proves the attractiveness of our country," Spanish Rugby Union (FER) President Juan Carlos Martín ‘Hansen’ added.
"We are delighted to host this historic match and happy to see San Mamés and Bilbao coming together to host rugby events of this magnitude, which undoubtedly enhances the growth of rugby in our country.”