Argentina veteran Julián Montoya will lead Los Pumas for the 50th time when he takes the field against Australia on Saturday afternoon.
His captaincy milestone headlines an exciting matchday squad for Sydney featuring three changes from last weekend's side that went down to the Wallabies 28-24 in overtime.
Watch the Wallabies take on Los Pumas live and on-demand via Stan Sport.
Argentina head coach Felipe Contepomi has promoted boom backrower Joaquín Oviedo to the starting pack with vice captain Pablo Matera named as a finisher.
"Pablo comes with a huge physical wear and tear and does things very, very well," Contepomi said to reporters in Sydney, when asked about the loose forward shift.
"We also have other players who can bring us the energy we need to start the game.
"A win or a loss, it's just a result. And then we try to always reset to zero and start the week, no matter whatever the result is the weekend before.
"We need to be better. But the squad is in good spirit and we had a very good week's training."
Lock Guido Petti has also earned a promotion with Force-bound Franco Molina moved the the bench.
Sevens star Rodrigo Isgro rounds out the starting changes and replaces Townsville try-scorer Bautista Delguy on the right wing.
Los Pumas currently sit third on the Rugby Championship ladder and need a win over the second-placed Wallabies at Allianz Stadium to keep their title hopes alive heading into a two-game home and away series against South Africa.
Montoya will sit one cap off the all-time Pumas captaincy record - 51 caps held by Agustín Creevy, with the hooker quick to acknowledge the 110-capped Puma legend.
"It's never a bad game when you play with the Pumas jersey," Montoya said.
"Obviously being captain is a huge pride, it's a very nice responsibility and I'm very grateful. What I like the most is playing for this team and wearing the jersey.
"I share with [Creevy] a big part of my career and I learnt a lot from him. We compete and he makes me better, I'm very grateful for that.
"[But] in terms of the number of caps, I think it's nice, but it's just a number for me.
"My biggest honour is to be captain of this team and this group of players."
Meanwhile, Australia have already named their matchday squad headlined by Tane Edmed's starting debut and the return of Queensland trio Hunter Paisami, Lukhan Salakaia-Loto and Josh Nasser.
The Wallabies-Los Pumas clash kicks off at 2pm AEST on Saturday 13 September via the Nine Network and Stan Sport.
ARGENTINA (1-15): Mayco Vivas, Julián Montoya, Joel Sclavi, Guido Petti, Pedro Rubiolo, Juan Martín Gonzalez, Marcos Kremer, Joaquín Oviedo, Gonzalo Garcia, Santiago Carreras, Mateo Carreras, Santiago Chocobares, Luciano Cinti, Rodrigo Isgro, Juan Cruz Mallia
RESERVES: Ignacio Ruiz, Boris Wenger, Franciso Coria Marchetti, Franco Molina, Pablo Matera (vc), Agustin Moyano, Justo Piccardo, Ignacio Mendy