France and England have been handed timely blows ahead of next month's Six Nations competition.
Les Blues will be without flanker Charles Ollivon after he said Tuesday a right knee injury had brought a premature end to his season.
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The former France skipper, 31, is to undergo an operation after sustaining the injury in the seventh minute of Toulon's 36-24 Top 14 victory over Racing 92 on Saturday.
"I have to stop doing what I love for the moment and I'll soon be operated on," Ollivon said on social media.
Ollivon said he would be back on the paddock "next season".
The flanker, capped 46 times by France, previously saw his career interrupted between 2017-19 with shoulder and scapula injuries, before snapping his left knee cruciate ligament in 2021.
Ollivon's absence follows that of another experienced member of Fabien Galthie's France squad, centre and defensive backline leader Gael Fickou, who will miss the start of Six Nations action with a broken thumb.
Meanwhile, Immanuel Feyi-Waboso is set to miss the 2025 Six Nations after reportedly opting to undergo shoulder surgery.
Feyi-Waboso dislocated his shoulder in Exeter's 28-10 defeat to Sale Sharks in December.
The Welsh-born is expected to go under the knife for surgery, with the winger expected in Andy Farrell's squad for the British and Irish Lions tour.
It comes after full-back George Furbank suffered a broken arm playing for Northampton.
France kick off their Six Nations campaign at home to struggling Wales at the Stade de France on January 31.
Meanwhile, England will begin their campaign with an away trip to Ireland.
