The Queensland Reds and NSW Waratahs resume their rivalry as the two teams face off at Suncorp Stadium.
The Waratahs got the better of the Reds in their opening round fixture, claiming a 36-12 victory in Sydney.
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But plenty has changed since, with the Reds flying high after their last-minute winner over the ACT Brumbies in Canberra.
Seru Uru and Tim Ryan bolster their starting side, out to make it six on the trot at Suncorp Stadium against the Waratahs.
For the Waratahs, there have been several changes following last week's heavy defeat to the Hurricanes, calling Jack Debreczeni, Sid Harvey and James Hendren into the starting side.
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Welcome to Rugby.com.au's coverage to the Queensland Reds-NSW Waratahs derby at Suncorp Stadium.
The visitors have been forced into a late change, with Charlie Gamble out, replaced by Jamie Adamson.
For once, the Reds might actually have a home game without rain, with the forecast promising (touch wood).
REDS (1-15): Aidan Ross, Josh Nasser, Zane Nonggorr, Seru Uru, Lukhan Salakaia-Loto, Joe Brial, Fraser McReight (c), Harry Wilson, Louis Werchon, Carter Gordon, Tim Ryan, Isaac Henry, Josh Flook, Filipo Daugunu, Jock Campbell
Replacements: Richie Asiata, George Blake, Jeffery Toomaga-Allen, Hamish Muller, Vaiuta Latu, Kalani Thomas, Harry McLaughlin-Phillips, Treyvon Pritchard
WARATAHS (1-15): Tom Lambert, Ethan Dobbins, Daniel Botha, Matt Philip (c), Angus Blyth, Clem Halaholo, Jamie Adamson, Pete Samu, Jake Gordon, Jack Debreczeni, Sid Harvey, Joey Walton, Triston Reilly, Max Jorgensen, James Hendren
Replacements: Ioane Moananu, Isaac Kailea, Siosifa Amone, Miles Amatosero, Leafi Talataina, Teddy Wilson, Lawson Creighton, Harry Potter
Referee: Ben O'Keeffe
Assistant Referees: Maggie Cogger-Orr, Warwick Lahmert
TMO: Richard Kelly
The Reds' clash with the Reds will be shown LIVE on Stan Sport.
Coverage will be live and ad-free on Stan Sport, starting at 7:00 pm with kickoff expected at 7:35 pm.