South Africa coach Rassie Erasmus has ditched six of his original Rugby Championship squad for a second-round match against Argentina in Mendoza this Saturday.
Out of the 35-man squad go backs Lwazi Mvovo, Jesse Kriel and Ross Cronje and forwards Marvin Orie, Jean-Luc du Preez and Sikhumbuzo Notshe.
A seventh absentee is flanker Cyle Brink, who had knee surgery last week and will be out of action for an undisclosed period.
The Springboks did not impress for much of a 34-21 victory over the Pumas in Durban this weekend and Erasmus has promised "four or five changes" for the reverse fixture.
Meanwhile Argentina have eased their self-imposed restriction on European-based rugby players to strengthen their squad for their match against South Africa.
The Pumas have called four new faces into their squad for next weekend's Rugby Championship match at home to the Springboks.
Argentina, who lost their opener 34-21 in Durban on Saturday, brought back Jeronimo de la Fuente after injury and called up backs Santiago Alvarez Fourcade and Santiago Carreras for the first time, the team announced via Twitter.
Uncapped hooker Facundo Bosch was also drafted in from his club side Agen in France.
The Argentines played the last two Rugby Championships without any European-based players but they have eased that self-imposed restriction this time in a bid to make themselves more competitive with the best of the southern hemisphere.
They play South Africa in Mendoza on Saturday.
The Pumas host the Springboks in Mendoza on Sunday morning, kicking off at 5:10am AEST, LIVE on FOX SPORTS.
Pumas to face Springboks in Mendoza
Santiago Alvarez Fourcade
Jeronimo De la Fuente
Santiago Garcia Botta
Santiago Gonzalez Iglesias
Juan Cruz Mallia
Javier Ortega Desio
Nahuel Tetaz Chaparro
Juan Pablo Zeiss
Springboks to travel to Mendoza
Siya Kolisi (capt)
Akker van der Merwe,
Marco van Staden
Pieter-Steph du Toit
Thomas du Toit
Faf de Klerk
Willie le Roux
Ivan van Zyl