A Waratah-laden Easts side couldn't get the better of Warringah in round two of Shute Shield.
Cody Walker, Ryan McCauley, Tom Staniforth, Will Harris, Mack Mason and Lalakai Foketi all started in a tough 37-14 loss to the Rats.
Rory O'Connor took the bragging rights with Warringah, playing a loosehead prop for the Northern Beaches side.
Monster South African lock Le Roux Roets came off the bench for Manly in a tight loss to Eastwood.
JP Sauni and John Folau both started on a tough day against Sydney Uni, with the defending champions fielding a side that included Waratahs backrower Locky Swinton at lock and squad member Angus Bell on the pine.
Mitch Short and Will Harrison combined in the halves for Randwick with James Ramm on the right wing but their influence wasn't enough to clinch a win over West Harbour.
Curtis Rona had a try for Southern Districts in a tight win over Gordon.
Easts 14 - Warringah 37
Eastwood 31 - Manly 27
Western Sydney 3- Sydney Uni 49
West Harbour 39 - Randwick 24
Gordon 27 - Southern Districts 31
QUEENSLAND PREMIER RUGBY
Reds rookie Josh Nasser played tighthead for UQ in a shock 70 -21 loss to Wests in Brisbane.
Flanker Tom Kibble found the line for GPS in a 24-14 win over Souths.
Last year's U20s player of the year, Fraser McReight,scored for Brothers in a dominant 61-14 victory over Norths, with new Reds 10 option Matt McGahan enjoying his first start and secnd game back from a broken leg.
Wests 70 - UQ 21
Souths 14 - GPS 24
Bond Uni 28 - Easts 32
Brothers 61 - Norths 14
JOHN I DENT CUP
Blake Enever started for Easts up against fellow Brumbies Connal McInerney and Faalelei Sione and it was the latter who took the edge with Royals.
Chance Peni crossed for Wests in a loss to the Uni-Norths Owls.
Uni-Norths Owls 25 - Wests 19
Easts 10 - Royals 31
FMG PREMIER GRADE
Force backrower Fergus Lee-Warner played no. 8 for the Southern Lions in a thrilling 26-20 win over Joondalup.
Harrison Orr found the line for ARKs in their win over Perth Bayswater.
Associates 35 - Palmyra 10
Kalamunda 41 - Coastal Cavaliers 3
UWQ 39 - Wanneroo 20
Wests 34 - Nedlands 25
Joondalup 20 - Southern Lions 26
Cottesloe 59 - Curtin Uni 0
ARKs 25 - Perth Bayswater 21