Karmichael Hunt had his first start for Souths but it wasn't enough to clinch a win for the Magpies, going down 34-27 to GPS in Queensland Premier Rugby.
Quade Cooper scored 12 of those 27 points but it was Reds rookie halfback James Tuttle who stole the show with a 14-point haul for GPS.
Nick Jooste booted 13 points playing at 10 for Norths, alongside Reds teammate no. 8 Reece Hewat, with Duncan Paiaaua coming off the bench.
Departing Reds hooker Andrew Ready and returning flanker Michael Gunn lined up for Easts against that trio, taking the points in that clash.
Rising lock Harry Hockings scored a try for UQ in a high-scoring win over Wests, with Lachlan Maranta at 13 for Wests.
Norths 23 - Easts 29
Sunnybank 17 - Bond Uni 48
Wests 40 - UQ 53
Souths 27 - GPS 34
Hugh Roach started at hooker for Eastwood as they went down in a narrow loss to West Harbour.
Ryan McCauley and Cody Walker packed down for Easts, with Mack Mason steering the ship at 10, but it was tighthead Shambeckler Vui who took the bragging rights, with Souths.
Manly had a second draw in as many weeks, unable to be split with Randwick.
Easts 30 - Souths 36
Manly 36 - Randwick 36
Parramatta 8 - Sydney Uni 29
West Harbour 33 - Eastwood 26
Gordon 14 - Warringah 83
Tayler Adams steered Moorabbin, playing alongside Rebels teammate Vaauli Faamausili around in a tight win over Melbourne Uni.
Hunter Paisami was at fullback for Harlequin, up against Esei Haangana, who was at lock for Melbourne.
Rebels forwards Sama Malolo and Tom Moloney started for Endeavour Hills, suffering a loss to Footscray.
Harlequin 41 - Melbourne 27
Box Hill 17 - Power House 25
Footscray 43 - Endeavour Hills 28
Moorabbin 27 - Melbourne Uni 26
JOHN I DENT CUP
Brumbies back Jordan Jackson-Hope played at inside centre for Tuggeranong in a big win over Queanbeyan in the John I Dent Cup.
Tuggeranong 37 - Queanbeyan 14
Royals 33 - Easts 7
Wests 5 - Gungahlin 29
FORTESCUE PREMIER GRADE
Force hooker Harry Scoble started for UWA in a win over ARKs, ahead of the Force's win over Apia on Saturday night.
UWA 24 - ARKS 17
Palmyra 18 - Perth Bayswater 0
Coastal Cavaliers 18 - Southern Lions 16