South Africa lock Franco Mostert has been recalled in the only change to the starting line-up for the Rugby Championship return match against Argentina in Mendoza Saturday.
The forward, a recent signing by English Premiership outfit Gloucester from the Lions, replaces Pieter-Steph du Toit, who drops to the bench.
In changes among the substitutes, tighthead prop Wilco Louw and lock RG Snyman come in and Thomas du Toit, Marvin Orie and Marco van Staden are omitted.
Coach Johan 'Rassie' Erasmus said: "Franco needed rest after the Super Rugby campaign and the June internationals against England and we did not consider him for Durban.
"He has been our first-choice number five lock and that is why is starting in Mendoza this Saturday."
South Africa came from nine points behind during the first half in Durban last Saturday to score a bonus-point 34-21 victory. They share first place with New Zealand.
Erasmus resisted the temptation to reshuffle his back row of flankers Francois Louw and captain Siya Kolisi and number eight Warren Whiteley, who were average last weekend.
"I want to build more continuity and this combination now has another opportunity to play together and gain more experience," he said.
South Africa found the going tough during two previous visits to Estadio Malvinas Argentinas in Mendoza, a western city at the foothills of the Andes mountains.
The Springboks scraped a 16-16 draw in 2012 -- the year the Pumas joined the southern hemisphere championship -- and won 22-17 the following season.
"We have always rated Argentina as a very powerful team and we felt the game in Durban was physical," said Erasmus.
"They are going to step it up and I think they will come hard at our mauling, scrums and the breakdowns."
Meanwhile, Tomas Lavanini replaces Matias Alemanno at lock in the only change to the Argentina starting line-up.
Alemanno replaces Lavanini on the bench, where there are three other changes with centre Jeronimo de la Fuente, scrum-half Tomas Cubelli and hooker Facundo Bosch promoted.
Utility back Santiago Gonzalez Iglesias, hooker Diego Fortuny and veteran scrum-half Martin Landajo drop out of the matchday 23 for the game at Estadio
Malvinas Argentinas.
Cubelli is back in the squad after a long absence having been injured against New Zealand in the Rugby Championship last year.
The Pumas will be seeking only a second home victory over the Springboks after one win, one draw and 11 losses in the South American nation since they first met there 25 years ago.
Hooker Agustin Creevy skippers a side that lost twice to Wales and once to Scotland at home during June before coming off second best to South Africa in Durban.
TEAMS
Argentina to face South Africa
1. Nahuel Tetaz Chaparro
2. Agustin Creevy
3. Juan Figallo
4. Guido Petti
5. Tomas Lavanini
6. Pablo Matera
7. Marcos Kremer
8. Javier Ortega Desio
9. Gonzalo Bertranou
10. Nicolas Sanchez
11. Ramiro Moyano
12. Bautista Ezcurra
13. Matias Moroni
14. Bautista Delguy
15. Emiliano Boffelli
Reserves
16. Facundo Bosch
17. Santiago Garcia Botta
18. Santiago Medrano
19. Matias Alemanno
20. Tomas Lezana
21. Tomas Cubelli
22. Jeronimo de la Fuente
23. Juan Cruz Mallia
Springboks to face Argentina
1. Tendai Mtawarira
2. Malcolm Marx
3. Franz Malherbe
4. Eben Etzebeth
5. Franco Mostert
6. Francois Louw
7. Siya Kolisi
8. Warren Whiteley
9. Faf de Klerk
10. Handre Pollard
11. Aphiwe Dyantyi
12. Andre Esterhuizen
13. Lukhanyo Am
14. Makazole Mapimpi
15. Willie le Roux
Reserves
16. Bongi Mbonambi
17. Steven Kitshoff
18. Wilco Louw
19. RG Snyman
20. Pieter-Steph du Toit
21. Embrose Papier
22. Lionel Mapoe
23. Damian Willemse