Argentina have been forced into a late change for their Rugby Championship clash with Australia when midfield regular Jeronimo de la Fuente failed a fitness test on Friday.
De La Fuente, who has started in every Pumas Test this year, injured his left leg in training and has been replaced by Santiago Gonzalez Iglesias.
Saturday's game will be his first start in almost a year.
Three-time rugby World Cup back Juan Martin Hernandez comes onto the reserves bench for a match in which the Pumas are out to redeem themselves.
They are at risk of failing to earn a competition point for the first time since joining the competition in 2012.
"We are failing to carry out the game plan," flanker Pablo Matera said.
"The system is not failing, it is us players who are failing."
Matera said they remain determined to beat the Wallabies, as they did in the same Malvinas Argentinas Stadium in 2014.
"If we beat Australia, we can finish the championship by beating a top team," he said.
"To beat Italy in November will not give us anything."
TEAM
Pumas team to face the Wallabies
1. Lucas Noguera
2. Agustin Creevy (c)
3. Nahuel Tetaz
4. Marcos Kremer
5. Matias Alemanno
6. Pablo Matera
7. Javier Ortega Desio
8. Tomas Lezana
9. Martin Landa
10. Nicolas Sanchez
11. Emiliano Boffelli
12. Santiago Gonzalez Iglesias
13. Matias Orlando
14. Matias Moroni
15. Joaquin Tuculet
Reserves
16. Julian Montoya
17. Santiago Garcia
18. Enrique Pieretto
19. Benjamin Macomme
20. Leonardo Senatore
21. Gonzalo Bertranou
22. Juan Martin Hernandez
23. Santiago Cordero
